年度盘点 – 2021质谱流式国内高分文献精选

Multi-Dimensional Organic Mass  Cytometry: Simultaneous Analysis of Proteins and Metabolites on Single Cells

Angewandte Chemie

1月25日

利用质谱流式分析单细胞蛋白和代谢情况

12.959

Galectin-9 interacts with PD-1 and TIM-3  to regulate T cell death and is a target for cancer immunotherapy

Nature Communications

2月5日

质谱流式在肿瘤免疫治疗中的应用

14.919

M-CSF, IL-6, and TGF-β promote generation of a new subset of tissue repair  macrophage for traumatic brain injury recovery

Science Advance

3月12日

质谱流式在创伤性脑损伤康复中的应用

16.806

Group-2 Innate Lymphoid Cells Promote  HCC Progression Through CXCL2-Neutrophil-Induced Immunosuppression

Hepatology

4月8日

质谱流式对肝细胞癌中ILC2s的研究

17.425

IFN-γ-dependent NK cell activation is essential to metastasis  suppression by engineered Salmonella

Nature Communications

5月5日

质谱流式在细菌感染免疫中的应用

12.121

Atractylenolide I enhances  responsiveness to immune checkpoint blockade therapy by activating tumor  antigen presentation

Journal of Clinical Investigation

5月17日

质谱流式在肿瘤免疫治疗中的应用

14.808

Cas9-Cleavage Sequences in Size-Reduced  Plasmids Enhance Nonviral Genome Targeting of CARs in Primary Human T Cells

Small Methods

5月21日

质谱流式在CAR-T细胞中的研究

12.13

Synergistic immunotherapy of  glioblastoma by dual targeting of IL-6 and CD40

Nature Communications

6月8日

质谱流式在胶质母细胞瘤免疫治疗中的应用

14.919

Applications of single-cell sequencing  in cancer research: progress and perspectives

Journal of Hematology & Oncology

6月9日

肿瘤研究单细胞分析技术综述

11.059

WSX1 act as a tumor suppressor in  hepatocellular carcinoma by downregulating neoplastic PD-L1 expression

Nature Communications

6月9日

WSX1下调肿瘤PD-L1的表达抑制肝癌

14.919

Expression of KLRG1 and CD127 defines  distinct CD8 + subsets that differentially impact patient outcome in  follicular lymphoma

Journal for ImmunoTherapy of Cancer

7月9日

质谱流式在滤泡性淋巴瘤中的应用

13.751

Topological analysis of hepatocellular  carcinoma tumour microenvironment based on imaging mass cytometry reveals  cellular neighbourhood regulated reversely by macrophages with different  ontogeny

Gut

7月21日

组织成像质谱流式分析肝细胞癌肿瘤微环境的研究

23.059

New Structure Mass Tag based on Zr-NMOF  for Multiparameter and Sensitive Single-Cell Interrogating in Mass Cytometry

Advanced Materials

7月26日

基于纳米金属有机框架的锆金属标签研究

30.849

Targeting epigenetic modifiers to  reprogram macrophages in nonresolving inflammation-driven atherosclerosis

European Heart Journal

8月17日

单细胞组学在动脉粥样硬化中的应用综述

29.983

Technological advances in cancer  immunity: from immunogenomics to single-cell analysis and artificial  intelligence

Signal Transduction and Targeted Therapy

8月20日

肿瘤微环境及肿瘤免疫研究单细胞分析技术综述

18.187

Fresh tissue multi-omics profiling  reveals immune classification and suggests immunotherapy candidates for  conventional chondrosarcoma

Clinical Cancer Research

8月23日

质谱流式分析软骨肉瘤免疫微环境表型

12.531

Distinct human Langerhans cell subsets  orchestrate reciprocal functions and require different developmental  regulation

Immunity

9月8日

质谱流式在皮肤免疫中的应用

31.745

GDF15 induces immunosuppression via CD48  on regulatory T cells in hepatocellular carcinoma

Journal for ImmunoTherapy of Cancer

9月9日

质谱流式对肝细胞癌免疫抑制微环境的研究

13.751

M6A Demethylase ALKBH5 Regulates PD-L1  Expression and Tumor Immunoenvironment in Intrahepatic Cholangiocarcinoma

Cancer Research

9月15日

质谱流式揭示ALKBH5在肝内胆管癌肿瘤免疫微环境中的复杂作用

12.051

M 6 A Demethylase ALKBH5 Regulates PD-L1  Expression and Tumor Immunoenvironment in Intrahepatic Cholangiocarcinoma

Cancer Research

9月15日

质谱流式在肝内胆管细胞癌中的应用

12.701

High-throughput single-cell RNA-seq data  imputation and characterization with surrogate-assisted automated deep  learning

Briefings in Bioinformatics

9月22日

生信算法分析质谱流式数据

11.662

Distinct immune signatures discriminate  between asymptomatic and presymptomatic SARS-CoV-2 pos subjects

Cell Research 封面文章

9月24日

质谱流式分析SARS-CoV-2无症状和症状前患者免疫模式

25.617

Sult2b1 deficiency exacerbates ischemic  stroke by promoting pro-inflammatory macrophage polarization in mice

Theranostics

11月1日

利用质谱流式研究野生型和Sult2b1-/- 缺血性中风小鼠中巨噬细胞的变化

11.556

Aptamer Probes Labeled with  Lanthanide-Doped Carbon Nanodots Permit Dual-Modal Fluorescence and Mass  Cytometric Imaging

Advanced Science

11月1日

镧系掺杂碳纳米点标记的适配体探针允许荧光和质谱流式成像

16.806

Deep phenotyping of T cell populations  under long-term treatment of tacrolimus and rapamycin in patients receiving  renal transplantations by mass cytometry

Clinical and Translational Medicine

11月21日

质谱流式深度研究肾移植患者他克莫司和雷帕霉素长期治疗下T细胞群表型

11.492